An effective bot has the ability to learn and save information in variables and lists. With Published bots the 'Save' action and 'Close me' (with save) action do not function.
I prime example of this would be a script that accesses a web portal and is prompted to update the password. The password update process can be scripted in the bot, but since the new password cannot be saved in the variables or credentials this function cannot be possible.
We have many processes that run multiple times a day and store information in variables and lists that it saves each time it runs. We have had to move all this information to EXCEL files since published bots cannot save themselves.